Instant Pot Mississippi Roast Recipe | Tender Spice-Crusted Pot Roast

This is the best Instant Pot Mississippi Pot Roast recipe — tender, melt-in-your-mouth beef with a mild tang from pepperoncini. Ready in just over an hour, it’s a flavorful, comforting meal that works for weeknights and leftovers taste even better.

Made with chuck or sirloin tip roast, jarred pepperoncini and their juice, powdered ranch dressing mix, beef broth, olive oil, garlic, onions, butter, and fresh herbs. Simple ingredients yield big flavor.

Why You Will Love This Recipe

• Fork-tender pot roast that stays juicy and flavorful.
• Classic comfort food that’s easy to prepare.
• The Instant Pot speeds up cooking so you don’t need hours to enjoy a roast.
• Great next-day leftovers — excellent for sandwiches, tacos, or reheated over mashed potatoes.

What’s Great About the Instant Pot

The Instant Pot is one of the most useful appliances for fast, tender results. It cooks cuts of meat quickly, can even cook from frozen, and the sauté function lets you brown meat and soften aromatics right in the same pot — fewer dishes and more flavor.

Ingredient List

See the printable recipe card below for exact measurements and full instructions.

• Chuck roast or sirloin tip roast – pick a marbled cut for best flavor and tenderness.
• Pepperoncini peppers and juice – jarred pepperoncini add mild tang and depth.
• Red onions – add a subtle sweetness when sautéed.
• Olive oil – for searing the roast.
• Seasonings – dry ranch dressing mix, minced garlic, fresh chives and dill, salt and pepper.
• Beef broth – low-sodium is fine if you prefer to limit salt.
• Salted butter – adds richness to the sauce; use real butter for best taste.

How To Make Instant Pot Mississippi Pot Roast

1. Pat the roast dry and season all over with salt and pepper.
2. Choose the sauté setting on the Instant Pot, add the oil, and heat until shimmering.
3. Sear the roast on all sides, about 7–10 minutes total, then remove it to a plate.
4. Add onions and garlic to the pot and cook, stirring, until softened, about 5 minutes. Press Cancel when done.
5. Pour in half the beef broth and scrape the bottom of the pot to deglaze and avoid a “Burn” warning.
6. Return the roast to the pot. Add the pepperoncini, remaining beef broth, butter, and dry ranch dressing mix. Secure the lid and set the steam valve to Sealing.
7. Select Manual or Pressure Cook and set 55 minutes. It will take about 10 minutes to come to pressure before the timer begins.
8. When cooking finishes, allow a natural pressure release for about 10 minutes, then open the lid.
9. Remove the roast, stir in chives, dill, and pepperoncini juice into the sauce.
10. Return the roast to the pot and shred with forks into large chunks. Toss with the sauce and serve over mashed potatoes or egg noodles.

Food Safety

Follow USDA guidelines for cooking roasts: cook beef to a safe internal temperature (145°F for roasts) measured with a food thermometer and allow meat to rest for at least three minutes before cutting or serving.

Recipe Tips

• Chuck roast is ideal, but sirloin tip, blade roast, or similar cuts work because pressure cooking makes the meat very tender.
• Always sear the meat first to lock in flavor and color.
• To reduce sodium, use unsalted butter and low-sodium beef broth.
• Use whole pepperoncini so they can be removed easily for picky eaters and to maintain texture during cooking.

How to Store Leftovers

Refrigerator: Store leftovers in an airtight container for up to 3 days.

Freezer: Cool completely, then place in a freezer-safe container or bag for up to 2 months.

How To Use Leftovers

Leftover roast is versatile — use it in soups, tacos, enchiladas, burritos, or make hearty sandwiches and sliders.

Serving Suggestions

Serve with creamy mashed potatoes, buttered egg noodles, corn on the cob, southern-style green beans, and soft dinner rolls to soak up the sauce.

Helpful Supplies and Tools

An Instant Pot accessory kit, a tempered glass lid for the Instant Pot, and a sturdy bake-and-serve dish are convenient tools to have on hand when making and serving pot roast.

I hope you enjoy this easy Instant Pot Mississippi Pot Roast. If you try it, please come back and leave a comment and rating — I love hearing how your meal turned out!